CRISPR /Cas‐mediated genome editing to treat EGFR ‐mutant lung cancer: a personalized molecular surgical therapy
Author:
Affiliation:
1. Department of Cardiothoracic Surgery Division of Thoracic Surgery Stanford University School of Medicine Stanford CA USA
2. VA Palo Alto Healthcare System Palo Alto CA USA
Publisher
EMBO
Subject
Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201506006
Reference10 articles.
1. American Cancer Society(2015)Cancer Facts and Figures 2015.Atlanta:American Cancer Society.
2. Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
3. Multiplex Genome Engineering Using CRISPR/Cas Systems
4. AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer
5. Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
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