One‐step CRISPR /Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice-Reference-Cited by-同舟云学术

One‐step CRISPR /Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice

Published:2018-08-07 Issue:18 Volume:37 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Lin Ying‐Cing¹,Pecetta Simone¹,Steichen Jon M²,Kratochvil Sven¹,Melzi Eleonora¹^ORCID,Arnold Johan¹,Dougan Stephanie K³,Wu Lin⁴,Kirsch Kathrin H¹,Nair Usha¹,Schief William R¹²,Batista Facundo D¹^ORCID

Affiliation:

1. Ragon Institute of MGH, MIT and Harvard Cambridge MA USA

2. Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center The Scripps Research Institute La Jolla CA USA

3. Dana‐Farber Cancer Institute Boston MA USA

4. Genome Modification Facility Department of Molecular and Cellular Biology Harvard University Cambridge MA USA

Funder

National Institute of Allergy and Infectious Diseases

Massachusetts General Hospital

International AIDS Vaccine Initiative

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201899243

Reference66 articles.

1. A requirement for lipid rafts in B cell receptor induced Ca 2+ flux

2. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus

3. Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope

4. B cells extract and present immobilized antigen: implications for affinity discrimination

5. Activation and Anergy in Bone Marrow B Cells of a Novel Immunoglobulin Transgenic Mouse that Is Both Hapten Specific and Autoreactive

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