CCR 5 deficiency impairs CD 4 + T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis-Reference-Cited by-同舟云学术

CCR 5 deficiency impairs CD 4 + T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis

Published:2020-06-11 Issue:15 Volume:39 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Martín‐Leal Ana¹,Blanco Raquel¹,Casas Josefina²³,Sáez María E⁴,Rodríguez‐Bovolenta Elena⁵,Rojas Itziar⁶,Drechsler Carina⁷⁸⁹,Real Luis Miguel¹⁰¹¹,Fabrias Gemma²³,Ruíz Agustín⁶¹²,Castro Mario¹³^ORCID,Schamel Wolfgang WA⁷⁸¹⁴^ORCID,Alarcón Balbino⁵^ORCID,Santen Hisse M⁵^ORCID,Mañes Santos¹^ORCID

Affiliation:

1. Department of Immunology and Oncology Centro Nacional de Biotecnología (CNB/CSIC) Madrid Spain

2. Department of Biological Chemistry Institute of Advanced Chemistry of Catalonia (IQAC‐CSIC) Barcelona Spain

3. CIBER Liver and Digestive Diseases (CIBER‐EDH) Instituto de Salud Carlos III Madrid Spain

4. Centro Andaluz de Estudios Bioinformáticos (CAEBi) Seville Spain

5. Department of Cell Biology and Immunology Centro de Biología Molecular Severo Ochoa (CBMSO/CSIC) Madrid Spain

6. Alzheimer Research Center Memory Clinic of the Fundació ACE Institut Català de Neurociències Aplicades Barcelona Spain

7. Signaling Research Centers BIOSS and CIBSS University of Freiburg Freiburg Germany

8. Department of Immunology Faculty of Biology University of Freiburg Freiburg Germany

9. Institute for Pharmaceutical Sciences University of Freiburg Freiburg Germany

10. Unit of Infectious Diseases and Microbiology Hospital Universitario de Valme Seville Spain

11. Department of Biochemistry, Molecular Biology and Immunology School of Medicine Universidad de Málaga Málaga Spain

12. CIBER Enfermedades Neurodegenerativas (CIBERNED) Instituto de Salud Carlos III Madrid Spain

13. Interdisciplinary Group of Complex Systems Escuela Técnica Superior de Ingeniería Universidad Pontificia Comillas Madrid Spain

14. Centre for Chronic Immunodeficiency (CCI) University of Freiburg Freiburg Germany

Funder

Instituto de Salud Carlos III

Comunidad de Madrid

Deutsche Forschungsgemeinschaft

“la Caixa” Foundation

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2020104749

Reference72 articles.

1. The Physical Properties of Ceramides in Membranes

2. Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains

3. CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

4. CCR5 Expression Levels Influence NFAT Translocation, IL-2 Production, and Subsequent Signaling Events during T Lymphocyte Activation

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