Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

Author:

Vlaming Hanneke1ORCID,McLean Chelsea M1,Korthout Tessy1,Alemdehy Mir Farshid2,Hendriks Sjoerd1,Lancini Cesare1,Palit Sander1,Klarenbeek Sjoerd3,Kwesi‐Maliepaard Eliza Mari1,Molenaar Thom M1,Hoekman Liesbeth3,Schmidlin Thierry T4,Altelaar AF Maarten45ORCID,Welsem Tibor1,Dannenberg Jan‐Hermen1,Jacobs Heinz2ORCID,Leeuwen Fred16ORCID

Affiliation:

1. Division of Gene Regulation Netherlands Cancer Institute Amsterdam The Netherlands

2. Division of Tumor Biology & Immunology Netherlands Cancer Institute Amsterdam The Netherlands

3. Experimental Animal Pathology Netherlands Cancer Institute Amsterdam The Netherlands

4. Biomolecular Mass Spectrometry and Proteomics Bijvoet Center for Biomolecular Research Utrecht Institute for Pharmaceutical Sciences Utrecht University and Netherlands Proteomics Centre Utrecht The Netherlands

5. Proteomics Facility Netherlands Cancer Institute Amsterdam The Netherlands

6. Amsterdam UMC location UvA Amsterdam The Netherlands

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

ZonMw

KWF Kankerbestrijding

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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