Topoisomerase I‐mediated cleavage at unrepaired ribonucleotides generates DNA double‐strand breaks-Reference-Cited by-同舟云学术

Topoisomerase I‐mediated cleavage at unrepaired ribonucleotides generates DNA double‐strand breaks

Published:2017-02 Issue:3 Volume:36 Page:361-373
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Huang Shar‐yin N¹,Williams Jessica S²,Arana Mercedes E²,Kunkel Thomas A²,Pommier Yves¹^ORCID

Affiliation:

1. Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology Center for Cancer Research National Cancer Institute NIH Bethesda MD USA

2. Genome Integrity and Structural Biology Laboratory National Institute of Environmental Health Sciences NIH Research Triangle Park NC USA

Funder

National Cancer Institute

National Institute of Environmental Health Sciences

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201592426

Reference61 articles.

1. A Saccharomyces cerevisiae RNase H2 Interaction Network Functions To Suppress Genome Instability

2. Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae

3. A Single 2′-Hydroxyl Group Converts B-DNA to A-DNA

4. NORF5/HUG1 Is a Component of the MEC1 -Mediated Checkpoint Response to DNA Damage and Replication Arrest in Saccharomyces cerevisiae

5. Ribonuclease H: the enzymes in eukaryotes

Cited by 56 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Endogenous base damage as a driver of genomic instability in homologous recombination-deficient cancers;DNA Repair;2024-09

2. Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNMPs, and impaired repair of TOP1-DNA crosslinks;Journal of Biological Chemistry;2023-12

3. RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart;The EMBO Journal;2023-10-19

4. Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase;Nature Communications;2023-03-03

5. Senataxin and RNase H2 act redundantly to suppress genome instability during class switch recombination;eLife;2022-12-21