Targeting CDK 2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors

Author:

Azimi Alireza1,Caramuta Stefano1,Seashore‐Ludlow Brinton2,Boström Johan3ORCID,Robinson Jonathan L4,Edfors Fredrik5,Tuominen Rainer1,Kemper Kristel6,Krijgsman Oscar6ORCID,Peeper Daniel S6ORCID,Nielsen Jens4ORCID,Hansson Johan1,Egyhazi Brage Suzanne1,Altun Mikael3ORCID,Uhlen Mathias5ORCID,Maddalo Gianluca5ORCID

Affiliation:

1. Department of Oncology‐Pathology Karolinska Institutet Karolinska University Hospital Stockholm Sweden

2. Chemical Biology Consortium Sweden, Science for Life Laboratory Division of Translational Medicine and Chemical Biology Department of Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden

3. Science for Life Laboratory Division of Translational Medicine and Chemical Biology Department of Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden

4. Department of Biology and Biological Engineering Chalmers University of Technology Göteborg Sweden

5. Science for Life Laboratory School of Biotechnology KTH Royal Institute of Technology Stockholm Sweden

6. Division of Molecular Oncology & Immunology The Netherlands Cancer Institute Amsterdam The Netherlands

Funder

Radiumhemmets Forskningsfonder

O. E. och Edla Johanssons Vetenskapliga Stiftelse

Stiftelsen Lars Hiertas Minne

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

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