The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis

Author:

Gasparini Giulio1ORCID,Saponaro Gianmarco1ORCID,Gasparini Daniela1,Foresta Enrico1,Azzuni Camillo1,Adduci Alessia2,Boniello Roberto1,Moro Alessandro1,De Angelis Paolo1,Di Nardo Francesco3ORCID,Damato Giuseppe1,Doneddu Piero1,Todaro Mattia1,Garagiola Umberto4ORCID,Pelo Sando1

Affiliation:

1. UOC Maxillo Facial Surgery, Policlinico Gemelli Foundation, Catholic University Medical School, Rome, Italy

2. Department of Anesthesiology and Intensive Care Medicine, Policlinico Gemelli Foundation, Catholic University Medical School, Rome, Italy

3. Institute of Public Health, Policlinico Gemelli Foundation, Catholic University Medical School, Rome, Italy

4. Department of Biomedical, Surgical and Oral Sciences, School of Dentistry, University of Milan, Milan, Italy

Abstract

The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this study, the authors have used Ropivacaine whose pharmaceutical kinetics allows the analgesic effect to be active for 60 to 90 minutes. In our research, we compared 8 groups of patients who have been given 3 principal pharmaceutical products: one group was given an anaesthetic drug, one had a topical medication administered which is often used for the treatment of aphthous lesions, and the last group was given a multivitamin. These pharmaceutical products were used alone and in various possible combinations in the 8 groups. The results of this study are very interesting and show that in all the groups that used anaesthetics there was more satisfaction on the patients’ part because their pain level became more manageable right after the first application of the drug and the patients could carry on with their normal lives.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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