Regioselective Synthesis of Dispiro Pyrrolizidines as Potent Antimicrobial Agents for Human Pathogens-Reference-Cited by-同舟云学术

Regioselective Synthesis of Dispiro Pyrrolizidines as Potent Antimicrobial Agents for Human Pathogens

Published:2013-09-10 Issue: Volume:2013 Page:1-8
ISSN:2314-629X
Container-title:ISRN Medicinal Chemistry
language:en
Short-container-title:ISRN Medicinal Chemistry

Author:

Sirisha N.¹^ORCID,Raghunathan R.¹

Affiliation:

1. Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, India

Abstract

Synthesis of a series of novel dispiro pyrrolizidines has been accomplished by 1,3-dipolar cycloaddition reaction of azomethine ylide generated from secondary amino acids and diketones with bischalcones. These compounds were evaluated for their antibacterial activity. Most of the synthetic compounds exhibited good antibacterial activity against microorganisms.

Publisher

Hindawi Limited

Subject

Computer Networks and Communications,Hardware and Architecture,Software

Link

http://downloads.hindawi.com/archive/2013/492604.pdf

Reference23 articles.

1. Methyl (S)-Lactate as a Chiral Auxiliary in the Asymmetric Synthesis of Bao Gong Teng A

2. A short dipolar cycloaddition approach to γ-lactam alkaloids from cynometra hankei

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