When a Seemingly Harmless Prescription Turns into Toxicity

Author:

Azmaiparashvili Zurab1ORCID,Lo Kevin Bryan1,Habib Nawal1,Hsieh Annie2

Affiliation:

1. Department of Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA

2. Department of Neurology, Albert Einstein Medical Center, Philadelphia, PA, USA

Abstract

Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. His condition was attributed to valacyclovir neurotoxicity, and initiation of appropriate supportive therapy was met with complete resolution of symptoms and normalization of cognitive function.

Publisher

Hindawi Limited

Subject

General Medicine

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