Successful Pregnancy in a Couple with Severe Male Factor Infertility after Selection of Sperm with Cytoplasmic Droplets-Reference-Cited by-同舟云学术

Successful Pregnancy in a Couple with Severe Male Factor Infertility after Selection of Sperm with Cytoplasmic Droplets

Published:2015 Issue: Volume:2015 Page:1-4
ISSN:2090-6684
Container-title:Case Reports in Obstetrics and Gynecology
language:en
Short-container-title:Case Reports in Obstetrics and Gynecology

Author:

Bellish Jenna¹,McCulloh David H.²³,Ahmad Khaliq²⁴,McGovern Peter G.¹²⁵

Affiliation:

1. Department of Obstetrics and Gynecology, Rutgers-New Jersey Medical School, 185 South Orange Avenue, MSB-E506, Newark, NJ 07103, USA

2. University Reproductive Associates, 214 Terrace Avenue, Hasbrouck Heights, NJ 07604, USA

3. New York University Langone Medical Center, NYU Fertility Center, 660 1st Avenue, New York, NY 10016, USA

4. Department of Obstetrics and Gynecology, Texas Tech University School of Medicine, Lubbock, TX 79430, USA

5. Department of Obstetrics and Gynecology, Mount Sinai St. Luke’s Roosevelt Hospital, 1000 Tenth Avenue, Suite 10C, New York, NY 10019, USA

Abstract

We present live births resulting from two separate IVF cycles in a couple in which ICSI was performed with sperm specifically selected for presence of small cytoplasmic droplets. These cycles followed previous cycles using standard sperm selection methods in which very poor embryo development and no pregnancies ensued. The male partner was diagnosed with severe male factor infertility including elevated DNA fragmentation.

Publisher

Hindawi Limited

Subject

Obstetrics and Gynaecology

Link

http://downloads.hindawi.com/journals/criog/2015/276931.pdf

Reference12 articles.

1. Novel association between sperm reactive oxygen species production, sperm morphological defects, and the sperm deformity index

2. Human sperm DNA integrity: correlation with sperm cytoplasmic droplets

3. Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa

4. Varicocele is associated with abnormal retention of cytoplasmic droplets by human spermatozoa

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2. Increased F2-Isoprostane Levels in Semen and Immunolocalization of the 8-Iso Prostaglandin F2α in Spermatozoa from Infertile Patients with Varicocele;Oxidative Medicine and Cellular Longevity;2018

3. Inherent Sperm Maturation: A Role for the Hermes Body (Cytoplasmic Droplet) of Sperm;Encyclopedia of Reproduction;2018