Vitamin D Intoxication and Nephrocalcinosis in a Young Breastfed Infant

Author:

Al-Kandari Abdullah1ORCID,Sadeq Hussain1ORCID,Alfattal Rita1,AlRashid Maryam2,Alsaeid Mayra3

Affiliation:

1. Department of Pediatrics, Al-Amiri Hospital, General Pediatrics Unit, Kuwait city, Kuwait

2. Department of Pediatrics, Al-Amiri Hospital, Pediatric Endocrine Unit, Kuwait city, Kuwait

3. Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait city, Kuwait

Abstract

Numerous studies were performed assessing the benefits and side effects of vitamin D. Vitamin D helps in regulating the calcium and phosphate metabolism leading to a healthy mineral and bone development. Vitamin D intoxication is an uncommon event that leads to hypercalcemia which can be associated with both immediate and late morbidities that can cause severe renal complications. Here, we present a case of a 4-month-old girl with a history of decreased feed and activity due hypercalcemia and high vitamin D level, which led to nephrocalcinosis. The patient received IV fluids, IV diuretics, methylprednisolone, and bisphosphonate in order to normalize the calcium level in blood. With clear verbal and written instructions for the dosage and administration of vitamin D supplements, as well as clear warnings of the potential risks of overdose, vitamin D intoxication could be an easily avoidable condition.

Publisher

Hindawi Limited

Subject

Endocrinology, Diabetes and Metabolism

Reference25 articles.

1. Vitamin D Supplementation and Risk of Toxicity in Pediatrics: A Review of Current Literature

2. Vitamin D: A Growing Perspective

3. The D-Lightful Vitamin D for Child Health

4. Vitamin D: Deficiency, Sufficiency and Toxicity

5. “Excess good can be dangerous”. A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D;K. K. Pandita;Clinical Cases in Mineral and Bone Metabolism,2012

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