Di-n-Butyl-, Tri-n-Butyl- and Triphenyltin dl-Terebates: Synthesis, Characterization and In Vitro Antitumour Activity-Reference-Cited by-同舟云学术

Di-n-Butyl-, Tri-n-Butyl- and Triphenyltin dl-Terebates: Synthesis, Characterization and In Vitro Antitumour Activity

Published:1997-01-01 Issue:4 Volume:4 Page:193-197
ISSN:0793-0291
Container-title:Metal-Based Drugs
language:en
Short-container-title:Metal-Based Drugs

Author:

Gielen Marcel¹,Ma Huairang¹²,Bouhdid Abdeslam¹,Dalil Hassan¹,Biesemans Monique¹³,Willem Rudolph¹³

Affiliation:

1. Department of General and Organic Chemistry, Faculty of Applied Sciences, Free University of Brussels V.U.B., Pleinlaan 2, Brussels B-1050, Belgium

2. Department of Chemistry, Northwest University, ShaanXi, Xian 710 069, China

3. High Resolution NMR Centre, Free University of Brussels V.U.B., Pleinlaan 2, Brussels B-1050, Belgium

Abstract

Di-n-butyltin, tri-n-butyltin and triphenyltin terebates were screened against several human tumour cell lines and found comparably or more active than carboplatin, cis-platin, 5-fluorouracil, methotrexate and doxorubicin, some reference compounds used clinically.

Publisher

Hindawi Limited

Subject

Inorganic Chemistry,Drug Discovery,Pharmacology,Toxicology

Link

http://downloads.hindawi.com/archive/1997/564582.pdf

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