The Estrogen Receptor Joins Other Cancer Biomarkers as a Predictor of Outcome

Author:

Leslie Kimberly K.1,Thiel Kristina W.1,Reyes Henry D.1,Yang Shujie1,Zhang Yuping1,Carlson Matthew J.1,Kumar Nirmala S.1,Dai Donghai D.1

Affiliation:

1. Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA

Abstract

Endometrial cancer, the most common gynecologic malignancy in the United States, is on the rise, and survival is worse today than 40 years ago. In order to improve the outcomes, better biomarkers that direct the choice of therapy are urgently needed. In this review, we explore the estrogen receptor as the most studied biomarker and the best predictor for response for endometrial cancer reported to date.

Funder

National Institutes of Health

Publisher

Hindawi Limited

Subject

Obstetrics and Gynecology

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