Affiliation:
1. Department of Biophysics, Faculty of Biology, Yerevan State University, A. Manoogian 1, 0025 Yerevan, Armenia
Abstract
The study of EtBr and H33258 interaction as well as EtBr and MB interaction with DNA has been carried out. It was revealed that, at joint interaction, the effect of two ligands on the change of melting thermodynamic parameters of EtBr-DNA-H33258 or EtBr-DNA-MB complexes is not an addition of separate interaction influences. It was shown that, at joint, binding of EtBr and MB with DNA competition occurs, while in the case of EtBr and H33258, the mutual strengthening of stabilizing effect of each of them on DNA double-stranded structure mainly takes place.
Subject
Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation,General Medicine
Cited by
5 articles.
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