An Unusual Cause of Secondary ITP in a 34-Year-Old Hispanic Male

Author:

Bangolo Ayrton1ORCID,Ahmed Mohamed1,Atoot Ali2,Mahmoud Ashraf3,Agbakwuru-Onyike Chibuzo1,Palad Maria Karina Larni Y.4,Sciarra Michael5,Atoot Adam1

Affiliation:

1. Department of Internal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, NJ, USA

2. Department of Anesthesia, Hackensack University Medical Center, Hackensack, NJ, USA

3. Department of Family Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, NJ, USA

4. University of the East Ramon Magsaysay, Quezon, Philippines

5. Department of Gastroenterology, Hackensack Meridian Health Palisades Medical Center, North Bergen, NJ, USA

Abstract

Secondary immune thrombocytopenic purpura (ITP) associated with Helicobacter pylori (H. pylori) infection has been described in the literature. It appears to have a geographic distribution; mostly encountered in countries with a higher prevalence for H. pylori such as Italy or Japan. H. pylori eradication has been recommended in the management of ITP with studies showing improvement in the platelet count in some patients. Substantial platelet count increases in patients with severe thrombocytopenia (platelet counts <30 × 103 microliter), however, are uncommon with H. pylori treatment alone. Here, we present a 34-year-old Hispanic male with worsening chronic thrombocytopenia that resolved following eradication of his H. pylori infection. Herein, we highlight a rare and reversible cause of secondary ITP. With this case report, we hope to encourage physicians to include H. pylori testing in the evaluation of thrombocytopenia.

Publisher

Hindawi Limited

Subject

Cell Biology,Developmental Biology,Embryology,Anatomy

Reference10 articles.

1. Disorders of platelets and vessel wall;B. A. Konkle,2018

2. Effect of eradication ofHelicobacter pylori on platelet recovery in patients with chronic idiopathic thrombocytopenic purpura: A controlled trial

3. Thrombocytopenia;K. Kaushansky,2021

4. Effects of eradication of Helicobacter pylori infection in patients with immune thrombocytopenic purpura: a systematic review

5. Helicobacter pylori acute gastritis: histological, endoscopical, clinical, and therapeutic features;G. A. Rocha;American Journal of Gastroenterology,1991

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