Refractory Cytomegalovirus Colitis in Common Variable Immunodeficiency Requiring Total Colectomy

Author:

Almushir Sulaiman1,Aljohani Faisal12,Qatomah Abdulrahman13ORCID

Affiliation:

1. Division of Gastroenterology and Hepatology, McGill University Health Centre, Montreal, QC, Canada

2. Department of Internal Medicine, Tabuk University, Tabuk, Saudi Arabia

3. Division of Gastroenterology and Hepatology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia

Abstract

Cytomegalovirus (CMV) colitis is an uncommon infection in immunocompetent hosts, usually occurring in the presence of an underlying immunodeficiency condition that allows for the reactivation of latent CMV infection. CMV colitis typically presents with persistent diarrhea, sometimes accompanied by bloody stools and nonspecific abdominal pain. We present the case of a 76-year-old woman known to have chronic CMV colitis, which was diagnosed in the context of underlying common variable immunodeficiency (CVID). Despite multiple attempts at managing CMV colitis, her symptoms persisted over the years. Ultimately, the patient required a pan colectomy due to refractory CMV colitis.

Publisher

Hindawi Limited

Subject

General Engineering

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