Predicting the Spread of Vessels in Initial Stage Cervical Cancer through Radiomics Strategy Based on Deep Learning Approach

Author:

Pareek Piyush Kumar1,Surendhar S Prasath Alais2,Prasad Ram3,Ramkumar Govindaraj4ORCID,Dixit Ekta5,Subbiah R.6,Salmen Saleh H.7,Almoallim Hesham S.8,Priya S. S.9,Jayadhas S. Arockia10ORCID

Affiliation:

1. Department of Computer Science and Engineering and Head of IPR Cell, Nitte Meenakshi Institute of Technology, Bengaluru, India

2. Department of Biomedical Engineering, Aarupadai Veedu Institute of Technology (AVIT), Chennai, TamilNadu, India

3. Department of Botany, Mahatma Gandhi Central University, Motihari 845401, Bihar, India

4. Department of Electronics and Communication Engineering, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

5. Department of Computer Science, S. S. D.Women’s Institute of Technology, Bathinda, Punjab, India

6. Department of Mechatronics Engineering, CMR Technical Campus, Hyderabad, India

7. Department of Botany and Microbiology, College of Science, King Saud University, PO Box 2455, Riyadh 11451, Saudi Arabia

8. Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, PO Box 60169, Riyadh 11545, Saudi Arabia

9. Department of Microbiology - Immunology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA

10. Department of EECE, St. Joseph University, Dares Salaam, Tanzania

Abstract

Novel methods and materials are used in healthcare applications for finding cancer in various parts of the human system. To select the most suitable therapy plan for individuals with domestically progressed cervical cancer, robustness metrics are required to estimate their early phase. The goal of the research is to increase the effectiveness of cervical cancer patients' detection by using deep learning-based radiomics assessment of magnetic resonance imaging (MRI). From March 2016 to November 2019, 125 patients with early-stage cervical cancer provided 980 dynamic X1 contrast-enhanced (X1DCE) and 850 X2 weighted imaging (X2WI) MRI images for training and testing. A convolutional neural network model was used to estimate cervical cancer state based on the specified characteristics. The X1DCE exhibited high discriminative outcomes than X2WI MRI in terms of prediction ability, as calculated by the confusion matrix assessment and receiver operating characteristic (ROC) curve approach. The mean maximum region under the curve of 0.95 was found using an attentive ensemble learning method that included both MRI sequencing (Sensitivity = 0.94, Specificity = 0.94, and accuracy = 0.96). Whenever compared with conventional radiomic approaches, the results show that a variety of radiomics based on deep learning might be created to help radiologists anticipate vascular invasion in patients with cervical cancer before surgery. Based on radiomics technique, it has proven to be an effective tool for estimating cervical cancer in its early stages. It would help people choose the best therapy method for them and make medical judgments.

Funder

King Saud University

Publisher

Hindawi Limited

Subject

General Engineering,General Materials Science

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