GIMAP Proteins in T-Lymphocytes-Reference-Cited by-同舟云学术

GIMAP Proteins in T-Lymphocytes

Published:2010-08-31 Issue: Volume:2010 Page:1-10
ISSN:2090-1739
Container-title:Journal of Signal Transduction
language:en
Short-container-title:Journal of Signal Transduction

Author:

Filén Sanna¹²,Lahesmaa Riitta¹

Affiliation:

1. Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Tykistökatu 6 B, P.O. BOX 123, 20520 Turku, Finland

2. Department of Pharmacology, Drug Development and Therapeutics, Drug Discovery Graduate School, University of Turku, Itäinen Pitkäkatu 4 B, 20520 Turku, Finland

Abstract

(GIMAPs) GTPase of the immunity associated protein family are a novel protein family of putative small GTPases. GIMAPs are mainly expressed in the cells of the immune system and have been associated with immunological functions, such as thymocyte development, apoptosis of peripheral lymphocytes and T helper cell differentiation. GIMAPs have also been linked to immunological diseases, such as T cell lymphopenia, leukemia and autoimmune diseases. In this review we examine the role of GIMAP proteins in T-lymphocyte biology.

Publisher

Hindawi Limited

Subject

Cell Biology,Cellular and Molecular Neuroscience,Biochemistry

Link

http://downloads.hindawi.com/archive/2010/268589.pdf

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