Biosynthesis of Secondary Metabolites Based on the Regulation of MicroRNAs

Author:

Hossain Rajib1ORCID,Quispe Cristina2,Saikat Abu Saim Mohammad3ORCID,Jain Divya4,Habib Arslan5,Janmeda Pracheta4,Islam Muhammad Torequl1,Radha 6,Daştan Sevgi Durna78,Kumar Manoj9ORCID,Butnariu Monica10ORCID,Cho William C.11ORCID,Sharifi-Rad Javad12ORCID,Kipchakbayeva Aliya13,Calina Daniela14ORCID

Affiliation:

1. Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh

2. Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile

3. Department of Biochemistry and Molecular Biology, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh

4. Department of Bioscience and Biotechnology, Banasthali Vidyapith, Rajasthan, India

5. Lab of Infectious and Molecular Immunology, School of Life Sciences, Fudan University, Shanghai, China

6. School of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India

7. Department of Biology, Faculty of Science, Sivas Cumhuriyet University, Sivas 58140, Turkey

8. Beekeeping Development Application and Research Center, Sivas Cumhuriyet University, Sivas 58140, Turkey

9. Chemical and Biochemical Processing Division, ICAR-Central Institute for Research on Cotton Technology, Mumbai 400019, India

10. Banat’s University of Agricultural Sciences and Veterinary Medicine “King Michael I of Romania” from Timisoara, Timisoara, Romania

11. Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong

12. Facultad de Medicina, Universidad del Azuay, Cuenca, Ecuador

13. Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty 050040, Kazakhstan

14. Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova 200349, Romania

Abstract

MicroRNA (miRNA), a noncoding ribonucleic acid, is considered to be important for the progression of gene expression in plants and animals by rupture or translational repression of targeted mRNAs. Many types of miRNA regulate plant metabolism, growth, and response to biotic and abiotic factors. miRNA characterization helps to expose its function in regulating the process of post-transcriptional genetic regulation. There are a lot of factors associated with miRNA function, but the function of miRNA in the organic synthesis of by-products by natural products is not yet fully elucidated. The current review is aimed at observing and characterizing miRNAs and identifying those involved in the functioning of the biosynthesis of secondary metabolites in plants, with their use in controlled manipulation.

Funder

International Centre for Empirical Research and Development

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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