Scaffolds in Vascular Tissue Engineering Research

Author:

Heng Jun W.1,Vijakumaran Ubashini1,Man Rohaina C.2,Sulaiman Nadiah1

Affiliation:

1. Centre for Tissue Engineering and Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000, Cheras, Kuala Lumpur, Malaysia

2. Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000, Cheras, Kuala Lumpur, Malaysia

Abstract

Scaffolds represent one of the key components in the tissue engineering triad. Construction of a vascular graft begins with the scaffold that acts as the base building material. Whether natural or synthetic, selecting the right scaffold material is essential to ensure the structural integrity of a graft. The structural integrity could further be strengthened with the addition of cells and regulatory signals that make up the whole tissue engineering triad. In this chapter, a selection of scaffold materials is discussed, and cell seeding strategies are later elaborated, covering the principle of the tissue engineering triad in vascular research.

Publisher

BENTHAM SCIENCE PUBLISHERS

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