Affiliation:
1. Laboratory of Protein Biochemistry, Biochemistry Department, Manipur University, Canchipur, Imphal 795003, India
Abstract
Background:
Lectins are class of proteins characterized by their ability to selectively bind
carbohydrate moieties of glycoproteins. Many invertebrate lectins, especially derived from hemolymph,
are being purified, and yet their functions and medical applications are subjects of major interest.
Methods:
Hemolymph lectins in invertebrates play a major role in protecting against many pathogens
and microbes. Further, many hemolymph lectins show anticancer properties towards various cancer
cell lines, which expresses globotriaosyl ceramides on their cell surface.
Results:
These vast repertoires of hemolymph lectins in recognizing and inhibiting the growth of various
harmful microbes and cancerous cells have spurred the biochemist to use them in histochemical
and cytochemical studies.
Conclusion:
The present review will address the biological roles and biomedical applications of hemolymph
lectin.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biotechnology
Reference73 articles.
1. Drickamer K.; Increasing diversity of animal lectin structures. Curr Opin Struct Biol 1995,5(5),612-616
2. Lis H.; Sharon N.; Lectins as molecules and as tools. Annu Rev Biochem 1986,55,35-67
3. Feroz Khan M.I.K.; Fungal lectins: Current molecular and biochemical perspectives. Int J Biologic Chem 2011,5,1-20
4. Ratcliffe N.A.; Invertebrate immunity-a primer for the non-specialist. Immunol Lett 1985,10(5),253-270
5. Maria Risoleta F.M.; Lectins, as non-self-recognition factors, in crustaceans 2000,191,23-44
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