Insights into Quinoline in Context of Conventional versus Green Synthesis

Abstract

Abstract: A relatively new field dubbed "green chemistry" seeks to achieve sustainability at the molecular level. This topic has received a lot of interest in recent years because of its ability to fulfill both environmental and economic goals through non-hazardous chemical innovation. A number of substituted quinoline derivatives were synthesized using microwave irradiation (MW), light irradiation, the presence of a non-biodegradable and recyclable catalyst, the presence of nanoparticles under solvent-free conditions, or the use of a green solvent. High target compound yields, fast reaction times, a simple workup process, the ability to reuse the catalyst, and environmentally favorable settings are all advantages of this effective approach. This study explores the synthesis of quinoline, a versatile heterocyclic compound with widespread applications in pharmaceuticals, agrochemicals, and material science. The focus is on comparing conventional and green synthesis methods and evaluating their respective advantages, drawbacks, and environmental impacts. The transition from conventional to sustainable green methodologies highlights the significance of reducing waste, energy consumption and toxic reagents in quinoline synthesis.