Cesium Carbonate (Cs2CO3) in Organic Synthesis: A Sexennial Update (2018 to Date)

Abstract

Cesium carbonate is an alkali carbonate salt that has numerous applications and has been proven to be a mild inorganic base in organic synthesis. It has garnered significant attention due to its practicality in C-H functionalization and heteroatom-heteroatom bond formation reactions, in addition to its application in conventional synthetic transformations. In this six-year update, we have examined the most important applications of Ca2CO3 in organic synthesis from 2018 to the present, including the scope of the reaction and providing detailed explanations of the underlying mechanisms.