Author:
Citak Mustafa,Masri Bassam A.,Springer Bryan,Argenson Jean-Noel,Kendoff Daniel O.
Abstract
Background and Purpose:
Antibiotic-loaded cement spacers are typically manufactured by surgeons in the operating room. However, if the infecting organism is known preoperatively, the cement spacer can be fabricated (Spacer-G® or the InterSpace® Hip) in advance. It is unclear if preformed hip spacers are superior to surgeon-made hip spacers in the treatment of periprosthetic joint infection following primary THA.
Methods:
A literature review of the peer-reviewed literature indexed by MEDLINE and Embase was performed to identify
studies reporting the outcomes of preformed and surgeon-made hip spacers in the treatment of infection following primary
total hip arthroplasty (THA). A total of 43 articles met the inclusion criteria and were included in the analysis to compare
the reinfection rate, Harris Hip Score (HHS) and spacer complication rates between surgeon-made and preformed hip
spacers.
Results and Interpretation:
The analyzed studies included a total number of 1631 infected THA cases (n=1027 surgeonmade;
n=604 preformed spacers). We found similar reinfection rates (6.0% surgeon-made, and 5.5% preformed spacers)
and similar mean HHS at latest follow-up after reimplantation (HHS=84.3 surgeon-made, and HHS=81.8 preformed
spacers) between both groups. However, patients treated with a surgeon-made articulating spacer had a higher spacer
fracture rate compared to preformed articulating spacer. The use of preformed articulating spacers in the treatment of
infected THA is not superior to surgeon-made articulating spacers regarding infection control and functional outcomes.
However, the use of surgeon-made antibiotic spacers increased the risk of spacer fracture.
Publisher
Bentham Science Publishers Ltd.
Reference46 articles.
1. Haaker R, Senge A, Krämer J, Rubenthaler F.
[Osteomyelitis after endoprostheses].
Orthopade
2004;
33
(4)
: 431-8.
2. D’Angelo F, Negri L, Zatti G, Grassi FA.
Two-stage revision surgery to treat an infected hip implant. A comparison between a custom-made spacer and a pre-formed one.
Chir Organi Mov
2005;
90
(3)
: 271-9.
3. D’Angelo F, Negri L, Binda T, Zatti G, Cherubino P.
The use of a preformed spacer in two-stage revision of infected hip arthroplasties.
Musculoskelet Surg
2011;
95
(2)
: 115-20.
4. Degen RM, Davey JR, Davey JR, Howard JL, McCalden RW, Naudie DD.
Does a prefabricated gentamicin-impregnated, load-bearing spacer control periprosthetic hip infection?
Clin Orthop Relat Res
2012;
470
(10)
: 2724-9.
5. Gil Gonzalez S, Marqués López F, Rigol Ramon P, Mestre Cortadellas C, Cáceres Palou E, León García A.
Two-stage revision of hip prosthesis infection using a hip spacer with stabilising proximal cementation.
Hip Int
2010;
20
(Suppl. 7)
: S128-34.
Cited by
39 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献