A Comprehensive Review on Current Perspectives of Flavonoids as Antimicrobial Agent

Author:

Gupta Tanya1,Kataria Ritu2,Sardana Satish3

Affiliation:

1. KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, 201206, India

2. G.V.M. College of Pharmacy, Sonipat, Haryana, India

3. Amity Institute of Pharmacy, Amity University, Haryana, Gurugram, India

Abstract

Abstract:Flavonoids are the secondary plant metabolites with diversities of pharmacological activities like antioxidant, anticancer, anti-inflammatory, hepatoprotective, free radical scavenging activity and antiviral activities. Flavonoids have also been proved as a major contributor to the antimicrobial phytochemicals. Being the major substituent of antibiotics today flavonoids has attained high attention as there is increase in persistence of untreatable microbial infections due to microbial resistance. This review demonstrates the screening, isolation of extracts and derivatisation of various flavonoids and their evaluation for antimicrobial potency. Recent advancements of various derivatives of flavonoids having antimicrobial activity has also been discussed in this review. This review helps researchers to get vast knowledge about flavonoids and also give an idea for current scenario of flavonoids and its applications as antimicrobial agent.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference66 articles.

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3. Hegazi A.G.; Abd E.I.; Hady F.K.; Abd Allah F.A.; Chemical composition of various propolis extracts. Pharmazie 1982,61,1103-1106

4. Cushnie T.P.T.; Lamb A.J.; Antimicrobial activity of flavonoids. Int J Antimicrob Agents 2005,26(5),343-356

5. Middleton E.; Chithan K.; In: The flavonoids advances in research since 1986 1993

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