Nano-nutraceuticals to Combat Oxidative Stress: Unlocking Newer Paradigms in Adjuvant Therapy

Author:

Pooja 1,Pandey Manisha1,Kumar Tarun1,Goswami Harsh1,Kumari Rasna1,Kumari Shivani1,Jain Neha2,Gorain Bapi3,Maurya Pawan Kumar4,Chawla Viney5,Chawla Pooja A.6

Affiliation:

1. Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, 123031, India

2. Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, India

3. Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India

4. Department of Biochemistry, Central University of Haryana, Mahendergarh, India

5. University Institute of Pharmaceutical Sciences and Research, BFUHS University, Faridkot, 151203, Punjab, India

6. University Institute of Pharmaceutical Sciences and Research, BFUHS University, Faridkot, 151203, Punjab, India

Abstract

Abstract: Nutraceuticals are products that provide both nutritional and therapeutic benefits. These compounds can slow the aging process and provide physiological effects shielding individuals from acute and chronic diseases. People's interests have shifted from allopathic to Ayurvedic to nutraceuticals in recent years. These are often common dietary supplements that have drawn customers worldwide because of their high nutritional safety and lack of adverse effects when used for a long time. Although conventional dosage forms, including pills, tablets, and semi-solids, are still available, they nevertheless have poorer bioavailability, less stability, and less effectiveness for targeted delivery of bioactives. The use of effective nanocomplex systems as nano-antioxidants using nanotechnology has become a promising field. Among its many uses, nanotechnology is mostly used to create foods and nutraceuticals that are more bioavailable, less toxic, and more sustainable. Additionally, it has been emphasized how precisely nano-pharmaceuticals for oxidative stress produce the desired effects. These improvements show improved antioxidant delivery to the target region, reduced leakage, and increased targeting precision. The outcomes demonstrated that oxidative stress-related illnesses can be effectively treated by lowering ROS levels with the use of nanonutraceuticals. The major ideas and uses of nano-nutraceuticals for health are outlined in this review, with an emphasis on reducing oxidative stress.

Publisher

Bentham Science Publishers Ltd.

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