Salivary Markers for Oral Cancer Detection

Author:

Markopoulos Anastasios K.,Michailidou Evangelia Z.,Tzimagiorgis Georgios

Abstract

Oral cancer refers to all malignancies that arise in the oral cavity, lips and pharynx, with 90% of all oral cancers being oral squamous cell carcinoma. Despite the recent treatment advances, oral cancer is reported as having one of the highest mortality ratios amongst other malignancies and this can much be attributed to the late diagnosis of the disease. Saliva has long been tested as a valuable tool for drug monitoring and the diagnosis systemic diseases among which oral cancer. The new emerging technologies in molecular biology have enabled the discovery of new molecular markers (DNA, RNA and protein markers) for oral cancer diagnosis and surveillance which are discussed in the current review.

Publisher

Bentham Science Publishers Ltd.

Subject

General Dentistry

Reference113 articles.

1. The international statistical classification of diseases and related health problems 1 In: World Health Organization; Geneva. 1992. (10 )

2. American Cancer Society. Cancer Facts and Figures 2007. Atlanta: American Cancer Society 2007.

3. Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2000, cancer incidence, mortality and prevalence worldwide, Version 10. Lyon: IARC Press 2001.

4. Peacock S, Pogrel A, Schmidt BL. Exploring the reasons for delay in treatment of oral cancer Am Dent Assoc 2008; 139 : 1346-52.

5. Schantz SP. Biologic markers, cellular differentiation, and metastatic head and neck cancer Eur Arch Otorhinolaryngol 1993; 250 : 424-8.

Cited by 70 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3