Affiliation:
1. Department Radiology, Fortis Escorts Heart Institute & Research Centre, New Delhi, Delhi 110025, India
Abstract
Introduction:
A 67-year-old female with no significant past medical history presented to the
critical care department with symptoms of encephalopathy.
Case Presentation:
The patient’s Main Concerns and the Important Clinical Findings: The patient
had a history of COVID -19 vaccination (recombinant ChAdOX1 nCoV-19) 14 days prior to the symptoms.
She underwent an MRI of the brain and cervical spine and a lumbar puncture.
The Primary Diagnoses, Interventions, and Outcomes:
The patient was examined and sent for an
MRI of the brain and cervical spine, followed by extensive blood and CSF investigations to rule out
any infective, paraneoplastic, connective tissue disorder, or inflammatory disorder. The patient was
given steroids, and a good response was reported. The primary diagnosis was made as vaccine-induced
ADEM.
Conclusion:
The clinical exam, location, sparse contrast enhancement, and CSF findings were all consistent
with an acute demyelinating event, and the history of vaccination, together with the clinical
situation, was found to be favourable for the development of acute disseminated encephalomyelitis.
Publisher
Bentham Science Publishers Ltd.
Subject
Radiology, Nuclear Medicine and imaging
Reference20 articles.
1. COVID live update: 230,329,713 Cases and 4,722,991 deaths from the coronavirus - worldometer. Available from:2021
2. Black S.B.; Law B.; Chen R.T.; The critical role of background rates of possible adverse events in the assessment of COVID-19 vaccine safety. Vaccine 2021,39(19),2712-2718
3. Drugs and Lactation Database (LactMed). Bethesda (MD): National Library of Medicine (US) COVID-19 vaccines 2006
4. Hatziantoniou S.; Maltezou H.C.; Tsakris A.; Poland G.A.; Anastassopoulou C.; Anaphylactic reactions to mRNA COVID-19 vaccines: A call for further study. Vaccine 2021,39(19),2605-2607
5. Schultz N.H.; Sørvoll I.H.; Michelsen A.E.; Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 vaccination. N Engl J Med 2021,384(22),2124-2130
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献