Affiliation:
1. Animal Stem Cells Lab, College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University,
Ludhiana, India
2. Division of Veterinary Medicine, Faculty of Veterinary Sciences & A.H., Sher-e-Kashmir University of Agricultural Sciences & Technology of Jammu, R.S. Pura, Jammu, J & K, India
Abstract
Abstract:
The utility of animal stem cells finds implications in enhancing milk, meat, and fiber production
and serving animal models for human diseases. Stem cells are involved in tissue development,
growth, and repair, and in regenerative therapy. Caprine embryonic stem cells (ESCs), induced pluripotent
stem cells (iPSCs) and other tissue-specific adult stem cells (ASCs) have tremendous potential for
their use in regenerative medicine. The application of goat ESCs, iPSCs, mammary stem cells (MaSC),
mesenchymal stem cells (MSCs), spermatogonial stem cells (SSCs) and others can find their implication
in increasing caprine production potential and human disease model. The onset of the disease and therapeutic
effects of stem cells of many human diseases like sub-fertility, joint conditions, intervertebral disc
defects, osteoarthritis, and chondrogenesis can be well studied in goats. Increasing evidence of MSCs and
their secreted factors have drawn the attention of animal scientists in regenerative medicine. This review
summarizes a comprehensive overview of research made on caprine stem cells and illustrates some potential
applications of stem cells in caprine regenerative medicine and their utility as a model animal in understanding
human diseases.
Publisher
Bentham Science Publishers Ltd.
Subject
General Medicine,Medicine (miscellaneous)