The Incredible Potential of Exosomes as Biomarkers in the Diagnosis of Colorectal Cancer

Abstract

Abstract: Colorectal cancer (CRC) is a common cancer that is one of the leading causes of cancer-related deaths around the world. The creation of new biomarkers for this disease is an important public health strategy for lowering the disease's mortality rate. According to new research, exosomes may be important sources of biomarkers in CRC. Exosomes are nanometer-sized membrane vesicles (30–200 nm) secreted by normal and cancer cells that transport RNA and proteins between cells and are thought to help with intercellular communication. Exosomes have been linked to CRC initiation and progression, and some differentially expressed RNAs and proteins in exosomes have been identified as potential cancer detection candidates. As a result, studying the relationship between exosomes and CRC may aid in the development of new biomarkers for the disease. This article discusses the importance of exosomes as biomarkers in the diagnosis of CRC, as well as their use in the treatment of CRC metastasis, chemoresistance, and recrudescence. We discuss the benefits and drawbacks of using exosomes as tumour markers, as well as the benefits and drawbacks of using exosomes as tumour markers. Method: The composites of the materials were synthesized using melt blending technique. The dielectric property of the produced materials were investigated using open ended coaxial probe technique. The dielectric constant values was used in the computational study of the composites using finite element method. Conclusion: From the electric field intensity, it was observed that the highest filler had the minimum transmitted intensity of 2185.87 v/m. Due to the high loss factor of 0.47 obtained for the 30 % filler content, waveguide terminators and other microwave components can be produced from this composite.