Affiliation:
1. School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China
2. School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, China
Abstract
Hydrogen therapy has recently received increasing attention as an emerging and promising therapeutic
technology due to its selective antioxidant property and cell energy regulatory capability in vivo. To solve
the low solubility issue of hydrogen, a variety of nanomaterials and devices for hydrogen supply have recently
been developed, aiming to increase the concentration of hydrogen in the specific disease site and realize controlled
hydrogen release and combined treatment. In this review, we mainly focus on the latest advances in using
hydrogen-generating devices and nanomaterials for hydrogen therapy. These developments include sustained
release of H2, controlled release of H2, versatile modalities of synergistic therapy, etc. Also, bio-safety
issues and challenges are discussed to further promote the clinical applications of hydrogen therapy and the development
of hydrogen medicine.
Funder
International Cooperation Project by Science and Technology Department of Sichuan Province
High-Level University Construction Project of Health Science Center, Shenzhen University
Special Funds for the Development of Strategic Emerging Industries in Shenzhen
Shenzhen Basic Research Program
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
Cited by
16 articles.
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