Affiliation:
1. Cardiology Department, Asklepeion Hospital, Athens, Greece
2. 2nd Prop Department of Internal Medicine, Aristotle University, Thessaloniki, Greece
Abstract
In heart failure (HF) patients, current European Society of Cardiology (ESC) guidelines recommend
the use of three loop diuretics (furosemide, torasemide, bumetanide) in order to not only reduce HF hospitalizations
but also improve symptoms and exercise capacity in patients with signs and/or symptoms of congestion.
In addition, for the first time in hypertensive patients, European Society of Hypertension (ESH) guidelines recommend
the use of torasemide. This review aimed to summarize the mode of action of loop diuretics, to present
their pharmacokinetic characteristics, and to discuss their place in the management of arterial hypertension
and heart failure, with special emphasis however on torasemide.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
Cited by
4 articles.
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