Nanoparticles from Actinobacteria: A Potential Target to Antimicrobial Therapy

Author:

Sivasankar Palaniappan1,Poongodi Subramaniam2,Seedevi Palaniappan1,Kalaimurugan Dharman1,Sivakumar Murugesan1,Loganathan Sivakumar1

Affiliation:

1. Department of Environmental Science, School of Life Sciences, Periyar University, Salem- 636011, Tamil Nadu, India

2. Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai - 608 502, Tamil Nadu, India

Abstract

Nanoparticles have gained significant importance in the past two decades, due to their multifaceted applications in the field of nanomedicine. As our ecosystems and habitats are changing due to global warming, many new diseases are emerging continuously. Treating these costs a lot of money and mostly ends up in failure. In addition, frequent use of antibiotics to control the emerging diseases has led the pathogens to develop resistance to antibiotics. Hence, the nanoparticles are targeted to treat such diseases instead of the costly antibiotics. In particular, the biosynthesized nanoparticles have received considerable attention due to their simple, eco-friendly and promising activity. To highlight, microbial mediated nanoparticles have been found to possess higher activity and thus have a promising role in antimicrobial therapy to fight against the emerging drug-resistant pathogens. In this context, this review article is aimed at highlight the role of nanoparticles in the field of nanomedicine and importance of actinobacteria in the nanoparticle synthesis and their need in antimicrobial therapy. This is a comprehensive review, focusing on the potential of actinobacteria-mediated nanoparticles in the field of nanomedicine.

Funder

Science and Engineering Research Board, Department of Science and Technology

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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