Advances in the Treatment of Autism Spectrum Disorder: Current and Promising Strategies

Author:

Yenkoyan Konstantin12,Ounanian Zadik1,Mirumyan Margarita122,Hayrapetyan Liana134,Zakaryan Naira2,Sahakyan Raisa2,Bjørklund Geir5

Affiliation:

1. Neuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia

2. Department of Biochemistry, Yerevan State Medical University after M. Heratsi, Yerevan, Armenia

3. Department of Radiation Oncology, Inselspital, Bern University Hospital and Department for BioMedical Research (DBMR), University of Bern, Switzerland

4. Graduate School for Cellular and Biomedical Sciences, University of Bern, Switzerland

5. Department of Research, Council for Nutritional and Environmental Medicine, Mo i Rana, Norway

Abstract

Abstract: Autism spectrum disorder (ASD) is an umbrella term for developmental disorders characterized by social and communication impairments, language difficulties, restricted interests, and repetitive behaviors. Current management approaches for ASD aim to resolve its clinical manifestations based on the type and severity of the disability. Although some medications like risperidone show potential in regulating ASD-associated symptoms, a comprehensive treatment strategy for ASD is yet to be discovered. To date, identifying appropriate therapeutic targets and treatment strategies remains challenging due to the complex pathogenesis associated with ASD. Therefore, a comprehensive approach must be tailored to target the numerous pathogenetic pathways of ASD. From currently viable and basic treatment strategies, this review explores the entire field of advancements in ASD management up to cutting-edge modern scientific research. A novel systematic and personalized treatment approach is suggested, combining the available medications and targeting each symptom accordingly. Herein, summarize and categorize the most appropriate ways of modern ASD management into three distinct categories: current, promising, and prospective strategies.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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