The Potential Role of Cardiokines in Heart and Kidney Diseases

Author:

Yang Ming1,Luo Shilu1,Yang Jinfei1,Chen Wei1,He Liyu1,Liu Di1,Wang Xi2,Sun Lin1

Affiliation:

1. Department of Nephrology, The Second Xiangya Hospital of Central South University, Changsha, China. Hunan Key Laboratory of Kidney Disease and Blood Purification, Changsha, Hunan, China

2. Department of Nutrition, Xiangya Hospital, Central South University, Changsha, Hunan, China

Abstract

Abstract: As the engine that maintains blood circulation, the heart is also an endocrine organ that regulates the function of distant target organs by secreting a series of cardiokines. As endocrine factors, cardiokines play an indispensable role in maintaining the homeostasis of the heart and other organs. Here, we summarize some of the cardiokines that have been defined thus far and explore their roles in heart and kidney diseases. Finally, we propose that cardiokines may be a potential therapeutic target for kidney diseases.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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