Affiliation:
1. Department of Pharmaceutical Sciences and Natural Products, Central University of Punjab, Bathinda-151001, India
Abstract
Abstract:
Background bacteria cause various infectious diseases and cause millions of deaths each
year. Bacteria are broadly classified based on the phenotypic and genotypic systems. Bacteria cause
resistance mainly by Plasmids, Inactivation of antibiotics, Target site modification, Preventing drug
uptake, Efflux pumps, and Biofilm. Plants have been used for thousands of years for their medicinal
properties to treat various diseases. Secondary metabolites like terpenes, alkaloids, phenolic compounds,
tannins, quinones, steroids, polyketides, aromatics, and peptides are plant-derived compounds
that possess antibacterial activity and decrease resistance by inhibition of biofilm formation,
Efflux pump [EP] inhibitors, attenuating bacterial virulence, and Immunomodulation activity. Phytoconstituents
synergism, combination therapy (Bio-enhancers), and herbal preparation benefit antibacterial
potential and decrease resistance.
Publisher
Bentham Science Publishers Ltd.
Subject
Complementary and alternative medicine,Drug Discovery