Affiliation:
1. Department of Internal Medicine, Spandan Multispeciality Hospital, Manjalpur, Vadodara, India
2. Senior Scientific Writer-Medical and Regulatory, Arkus Research Pvt. Ltd., Ahmedabad, India
Abstract
Abstract:
Diabetic patients with chronic kidney disease have a high risk of developing cardiovascular
disease-related mortality and morbidity compared to non-diabetic chronic kidney disease
patients. The Majority of chronic kidney disease patients with diabetes remain undiagnosed and
have a higher incidence of cardiovascular comorbidities even when they do not progress to endstage
renal failure. Both traditional cardiovascular risk factors and non-traditional cardiovascular
risk factors are known to be present in a higher magnitude in diabetic patients with chronic kidney
disease and are known to partially account for the increased incidence of cardiovascular disease
compared to non-diabetic chronic kidney disease patients. Moreover, there is no definitive evidence
for potential therapeutic treatment options for cardiovascular disease among diabetic patients
with chronic kidney disease, as these patients have often not been included in major cardiovascular
trials. Therefore, there is a need to recognize diabetic patients with chronic kidney disease
patients having a high cardiovascular disease risk for definite and immediate medical attention at
an individual patient level. Increased awareness, timely diagnosis, and intervention with respect to
control these plays a pivotal role in avoiding undesirable cardiovascular disease events and lead to
improved treatment outcomes among these patients. Further research is warranted to understand
the risk factors for cardiovascular disease and to develop and implement preventive and treatment
strategies to decrease the high morbidity and mortality among diabetic patients with chronic kidney
disease. This review summarizes the available epidemiological data, and risk factors, discusses
clinical presentations, and suggests prevention and management strategies for cardiovascular disease
risk among diabetic patients with chronic kidney disease.
Publisher
Bentham Science Publishers Ltd.
Subject
Cardiology and Cardiovascular Medicine,Pharmacology,Hematology
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