Affiliation:
1. Department of Oncology, Shanghai Medical College, Fudan University, No. 270 DongAn Road, Shanghai 200032, China
Abstract
Background:
Propofol, a widely used intravenous anesthetic agent, is traditionally applied for sedation
and general anesthesia.
Explanation:
Recent attention has been drawn to explore the effect and mechanisms of propofol against cancer
progression in vitro and in vivo. Specifically, the proliferation-inhibiting and apoptosis-inducing properties of
propofol in cancer have been studied. However, the underlying mechanisms remain unclear.
Conclusion:
This review focused on the findings within the past ten years and aimed to provide a general overview
of propofol's malignance-modulating properties and the potential molecular mechanisms.
Publisher
Bentham Science Publishers Ltd.
Subject
Cancer Research,Pharmacology,Molecular Medicine
Cited by
30 articles.
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