Recent Developments in Medicinal Chemistry and Therapeutic Potential of Anti-Cancer PROTACs-Based Molecules
Author:
Affiliation:
1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China
2. Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan
Abstract
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Reference219 articles.
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3. Xi M.; Chen Y.; Yang H.; Xu H.; Du K.; Wu C.; Xu Y.; Deng L.; Luo X.; Yu L.; Wu Y.; Gao X.; Cai T.; Chen B.; Shen R.; Sun H.; Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation. Eur J Med Chem 2019,174,159-180
4. Coux O.; Tanaka K.; Goldberg A.L.; Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 1996,65(1),801-847
5. Bhattacharyya S.; Yu H.; Mim C.; Matouschek A.; Regulated protein turnover: Snapshots of the proteasome in action. Nat Rev Mol Cell Biol 2014,15(2),122-133
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1. WITHDRAWN: Targeted protein degradation: A promising approach for cancer treatment;Journal of Pharmaceutical Analysis;2023-09
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