Current Overview on the Potency of Natural Products for Modulating Myeloid-derived Suppressor Cells Dependent Cold Tumors-Reference-Cited by-同舟云学术

Current Overview on the Potency of Natural Products for Modulating Myeloid-derived Suppressor Cells Dependent Cold Tumors

Published:2022-12 Issue:40 Volume:29 Page:6197-6216
ISSN:0929-8673
Container-title:Current Medicinal Chemistry
language:en
Short-container-title:CMC

Author:

Malla RamaRao¹²^ORCID,Pappu Lalitha³,Amajala Krishna Chaitanya²,Kamal Mohammad Amjad⁴⁵⁶⁷^ORCID

Affiliation:

1. Cancer Biology Laboratory, Department of Biochemistry and Bioinformatics, GIS, GITAM (Deemed to be University), Visakhapatnam 530045, Andhra Pradesh, India

2. Department of Biochemistry and Bioinformatics, GIS, GITAM (Deemed to be University), Visakhapatnam 530045, Andhra Pradesh, India

3. Department of Microbiology and FST, GIS, GITAM (Deemed to be University), Visakhapatnam 530045, Andhra Pradesh, India

4. Institute for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Sichuan, China

5. King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia

6. Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh

7. Enzymoics, 7 Peterlee Place, Hebersham NSW 2770; Novel Global Community Educational Foundation, Australia

Abstract

Abstract: Ample data pertaining to the use of MDSCs have been documented. However, the potency of natural products in targeting MDSCs in the light of the tumor immune microenvironment (TME) has not been discussed vividly. The current review is an amalgamation of the documented literature pertaining to the effectiveness of various natural products supported by in silico experimental data. The combination of bioinformatics to wet bench experimentation with natural products against cancer specifically targeting MDSCs can be a promising approach to mitigate cancer.

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine

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