The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic

Author:

Kumar Rajesh1ORCID,Harilal Seetha1ORCID,Al-Sehemi Abdullah G.2,Mathew Githa Elizabeth3ORCID,Carradori Simone4ORCID,Mathew Bijo5ORCID

Affiliation:

1. Department of Pharmacy, Kerala University of Health Sciences, Thrissur, Kerala, India

2. Research center for Advanced Materials Science, King Khalid University, 61413 Abha, Saudi Arabia

3. Department of Pharmacology, Grace College of Pharmacy, Palakkad, India

4. Department of Pharmacy, “G. d’Annunzio” University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy

5. Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, AIMS Health Sciences Campus, Kochi-682 041, India

Abstract

COVID-19, a type of infection that emerged in Wuhan, has become a pandemic affecting people worldwide and is rapidly spreading and evolving. Day by day, the confirmed cases and deaths are increasing many folds. SARS-CoV-2 is a novel virus; therefore, limited data are available to curb the disease. Epidemiological approaches, such as isolation, quarantine, social distancing, lockdown, and curfew, are being employed to halt the spread of the disease. Individual and joint efforts all over the world are producing a wealth of data and information which are expected to produce therapeutic strategies against COVID-19. Current research focuses on the utilization of antiviral drugs, repurposing strategies, vaccine development, as well as basic to advanced research about the organism and the infection. The review focuses on its life cycle, targets, and possible therapeutic strategies, which can lead to further research and development of COVID-19 therapy.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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