Quantitative Analysis for Chinese and US-listed Pharmaceutical Companies by the LightGBM Algorithm

Author:

Zheng Wenwen1,Li Junjun2,Wang Yu2,Ye Zhuyifan2,Zhong Hao2,Kot Hung Wan3,Ouyang Defang2,Chan Ging2

Affiliation:

1. Department of Clinical Laboratory, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

2. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China

3. Faculty of Business Administration, University of Macau, Macau, China

Abstract

Aim: This article aims to quantitatively analyze the growth trend of listed pharmaceutical companies in the US and China by a machine learning algorithm. Background: In the last two decades, the global pharmaceutical industry has faced the dilemma of low research & development (R&D) success rate. The US is the world's largest pharmaceutical market, while China is the largest emerging market. Objective: To collect data from the database and apply machine learning to build the model. Method: LightGBM algorithm was used to build the model and identify the factor important to the performance of pharmaceutical companies. Results: The prediction accuracy for US companies was 80.3%, while it was 64.9% for Chinese companies. The feature importance shows that the net profit growth rate and debt liability ratio are significant in financial indicators. The results indicated that the US may continue to dominate the global pharmaceutical industry, while several Chinese pharmaceutical companies rose sharply after 2015 with the narrowing gap between the Chinese and US pharmaceutical industries. Conclusion: In summary, our research quantitatively analyzed the growth trend of listed pharmaceutical companies in the US and China by a machine learning algorithm, which provide a novel perspective for the global pharmaceutical industry. According to the R&D capability and profitability, 141 US-listed and 129 China-listed pharmaceutical companies were divided into four levels to evaluate the growth trend of pharmaceutical firms.

Funder

Macau FDCT Research Grant

University of Macau Research Grant

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Molecular Medicine,General Medicine

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