Review on Analytical Methodologies, Chemical and Therapeutic Perspectives of Curcumin: A Ubiquitous Natural Molecule

Author:

Shah Umang kumar1,Patel Deep1,Dalsania Drashti1ORCID,Patel Mehul1ORCID,Patel Meghana1ORCID,Patel Ashish1ORCID,Solanki Nilay1ORCID,Patel Swayamprakash1ORCID,Patel Samir1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry and Analysis, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology (Charusat), Charusat Campus, Changa 388421, India

Abstract

Abstract: Curcumin is a lipophilic polyphenolic yellow compound extracted from Curcuma longa Linn. (turmeric) rhizome with a broad spectrum of pharmacological and medicinal properties as propounded by several in vivo, in vitro, and clinical studies. Considerable research over the past century has been extensively carried out on chemical, biological, and analytical perspectives of curcumin. Nowadays, curcumin is widely used in food and pharmaceutical formulations due to its excellent health benefits. Therefore, characterization and quantification of curcuminoids in nutraceuticals and pharmaceuticals are required to measure their quality control parameters to address issues related to processing and storage. This review article specifies the current exploration of analytical methodologies used to extract and quantify curcuminoids in different matrices. Moreover, this review offers phytochemistry, synthetic and biosynthetic pathways, extraction methodologies, degradation and metabolism pathways, and health benefits of the curcumin scurrying from the kitchen shelf toward the clinic.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics

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