Postoperative Clinical Monitoring After Morphine Administration: A Retrospective Multicenter Practice Survey
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Published:2019-05-22
Issue:2
Volume:14
Page:140-146
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ISSN:1574-8863
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Container-title:Current Drug Safety
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language:en
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Short-container-title:CDS
Author:
Raft Julien1, Podrez Kévin2, Baumann Cédric3, Richebé Philippe1, Bouaziz Hervé2
Affiliation:
1. Department of Anesthesiology and Pain Medicine, University of Montreal, Maisonneuve-Rosemont Hospital, 5415 Boulevard de l'Assomption, Montreal, QC H1T2M4, Canada 2. Department of Anesthesiology and Intensive Care, University Hospital of Nancy, 29, avenue du Marechal-de-Lattre-de-Tassigny, 54035 Nancy Cedex, France 3. Clinical Research Support Facility PARC, UMDS, University Hospital of Nancy, Vandoeuvre-les-Nancy, France
Abstract
Background:The objective of this survey was to describe the clinical monitoring practically used after intravenous, subcutaneous or neuraxial (epidural or intrathecal) administration of morphine.Methods:It was a descriptive, retrospective, multicenter (10 hospitals) survey based on the medical charts’ analysis, which evaluated the postoperative clinical monitoring after morphine administration.Results:Morphine was delivered intravenously (69%), intrathecally (19%), epidurally (10%) and/or subcutaneously (12%). Clinical monitoring protocols and protocols for the management of side effects were both present in 60% (n=6/10), only one of the two types of protocols in 10% (n=1/10) and both absent in 30% (n=3/10). Protocols for the management of respiratory depression and consciousness evaluation were present in 70% of cases (n=7/10). These events were reported on medical records without any prescription or protocol in 35% (n=14/40) and 37,5% (n=15/40) respectively. Prescriptions for respiratory rate evaluation and clinical monitoring of consciousness were in agreement with only 20% of the medical data and medical records. Different levels of respiratory rate were observed: 43% (n=3/7) below 8/min, 43% (n=3/7) below 10/min and 14% (n=1/7) below 12/min. Clinical monitoring was not performed in 31% (n=31/100) for consciousness and in 35% (n=35/100) for respiratory rate. Pulse oximeter was used in 48% (n=48/100) of patients. Capnography was never used. Respiratory depression occurred in 1% (n=1/100) of cases.Conclusion:This survey emphasizes an important disparity in the prescription of medical monitoring and a lack of use of protocols when morphine is administered. It demonstrates the need for a standardization of protocols according to the existing guidelines.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology (medical),Pharmacology,Toxicology
Reference30 articles.
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