Celecoxib Catalyzed the Coupling Reaction of Epoxide and CO2

Author:

Wu Ling1,Xia Xiaocheng2,An Wenying2,Cui Wenshan2,Liu Yue2,Lv Wei2,Wu Fengtian2

Affiliation:

1. Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices, East China University of Technology, Nanchang, 330013, China

2. Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices, East China University of Technology, Nanchang, 330013, China

Abstract

Abstract: In this study, high yields of various cyclic carbonates are obtained by employing the drug celecoxib to promote the coupling reaction of CO2 and epoxide using tetrabutylammonium bromide. This strategy enables the synthesis of benzoic acid, phenylpropiolic acid, and 2, 4- quinazolinedione. In addition, the model reaction mechanism is proposed.

Funder

State Key Laboratory of Heavy Oil Processing, China University of Petroleum

National (Provincial and University Level) College Students’ Innovation and Entrepreneurship Training Program, China

Jiangxi Provincial Department of Education Science and Technology Project

Opening Project of Jiangxi Province Key Laboratory of Synthetic Chemistry

Opening Project of Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices

Experimental Development Research Project of East China University of Technology

Publisher

Bentham Science Publishers Ltd.

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