Ultrasonic Preparation and Reactivity of 4,5-dihydro-1H-pyrazole Derivatives
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Published:2021-01-08
Issue:
Volume:17
Page:
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ISSN:1570-1786
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Container-title:Letters in Organic Chemistry
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language:en
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Short-container-title:LOC
Author:
Guesmi Ahlem1,
Ben Hamadi Naoufel1
Affiliation:
1. Chemistry Department, College of Science, IMSIU (Imam Mohammad Ibn Saud Islamic University), Riyadh 11623, Saudi Arabia
Abstract
:
The regiospecific synthesis of 1H-pyrazole derivatives has been accomplished through the 1,3-dipolar cycloaddition of aryldiazoalkane to but-3-en-2-one. A convenient and inexpensive ultrasound-assisted preparation of cyclopropenes
in good yields has been realized. The effect of solvent, ultrasonic power, frequency, reaction time and temperature of cyclopropenation were studied and the order of yield indicates Ultrasound, 25 KHz > Ultrasound, 40 KHz > conventional
synthesis method.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry