Zn(OAc)2•2H2O-Catalyzed Betti Base Synthesis under Solvent-free Conditions-Reference-Cited by-同舟云学术

Zn(OAc)2•2H2O-Catalyzed Betti Base Synthesis under Solvent-free Conditions

Published:2022-01 Issue:1 Volume:19 Page:14-18
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Alam M. Mujahid¹^ORCID,Bollikolla Hari B.²^ORCID,Varala Ravi³^ORCID

Affiliation:

1. Department of Chemistry, College of Science, King Khalid University, PO Box 9004, Abha 61413, Saudi Arabia

2. Department of Chemistry, Acharya Nagarjuna University, Guntur-522510, Andhra Pradesh, India

3. Scrips Pharma, Mallapur, Hyderabad-500 076, Telangana, India

Abstract

: Zn(OAc)2•2H2O-catalyzed one-pot multicomponent reaction of Betti bases using β- naphthol, aldehydes, and amines, under neat conditions in moderate to excellent yields (68- 96%) is reported in this study. This synthetic protocol offers several advantages, such as operational simplicity, shorter reaction period, high yields, and easy work-up procedures.

Funder

General Research Project King Khalid University

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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