Affiliation:
1. Department of Chemistry, Lahore College for Women University, Lahore, Pakistan
2. Institute of Chemistry, University of the Punjab, Lahore, Pakistan
Abstract
The structural diversity of spiro heterocycles has achieved an extensive attention of organic chemists due to their vast synthetic applications. Among these, spiropyrazolines are gaining considerable prominence due to their biological and pharmacological activities, electrophotographic photosensitivity as well as their application as beneficial synthons for spirocyclopropanes, cyclobutanes, pyrrolidinones, pyrazoles, 3-amino oxindoles and several natural products molecular architecture. In view of all these, this review aims to provide the classical and advanced regioselective approaches as well as synthetic applications of spiropyrazolines. The key reactions for its synthesis are 1,3-dipolar cycloaddition and condensations that are described completely in this piece of work.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Reference109 articles.
1. Jedlovska E, Levai A, Toth G, Balazs B. Fisera. L.
2. Dadiboyena S, Hamme AT.
3. Rahman MA, Siddiqui AA.
4. Levai A, Simon A, Jenei A, Kalman G, Jeko J, Toth G.
5. Farghaly TAE, Abbas IM, Hassan WMI. Lotfy. M.S.
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