Affiliation:
1. School of Mongolian Medicine, Inner Mongolian Medical University, Hohhot, China
2. School of Pharmacy, Inner Mongolian Medical University, Hohhot, China
Abstract
Abstract:
The stratum corneum continues to pose the biggest obstacle to transdermal drug delivery.
Chemical penetrant, the first generation of transdermal drug delivery system, offers a lot of potential. In
order to fully examine the permeation mechanism of 1,8-cineole, a natural monoterpene, this review
summarizes the effects of permeation-enhancing medications on drugs that are lipophilic and hydrophilic
as well as the toxicity of this substance on the skin and other tissues. For lower lipophilic drugs,
1,8-cineole appears to have a stronger osmotic-enhancing impact. An efficient and secure tactic would
be to combine enhancers and dose forms. 1,8-cineole is anticipated to be further developed in the transdermal
drug delivery system and even become a candidate drug for brain transport due to its permeability
and low toxicity.
Funder
National Natural Science Foundation of China
Inner Mongolia Natural Science Foundation of China
Inner Mongolia Medical University Mongolian Pharmacy "First-class Discipline" scientific research project
Scientific and Technological Innovative Research Team for Inner Mongolia Medical University of Bioanalysis of Mongolian medicine’s
University Youth Science and Technology Talent Program
Publisher
Bentham Science Publishers Ltd.
Cited by
1 articles.
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