Dietary Polyphenols in the Intervention of Gestational Diabetes

Abstract

Background: The impact of gestational diabetes mellitus GDM is severe since it is directly associated with the detrimental intra-uterine environment, which may lead to enhanced risk of development of fetal metabolic disorders and affects mother and offspring both. Plant derived polyphenols are reported for their protective roles against a variety of human diseases; however, the impact of adherence to polyphenols on the risk of GDM has not been exhaustively reviewed. Objective: Aim of this review is to summarize relevant studies linking polyphenols and polyphenol rich dietary patterns by carefully considering the mechanisms of their action to the risk of GDM and its management. Method: Data from PubMed, ScienceDirect, and Springer online databases and updates from the Indian Council of Medical Research (ICMR) were studied. Conclusion: Present review provides a comprehensive report on the association between plant polyphenols and lower risk of GDM, suggesting that polyphenol-rich dietary patterns may be important in preventing the development of GDM and its healthy management.